Green Fluorescent Protein is a Suitable Reporter of Tumor Hypoxia Despite an Oxygen Requirement for Chromophore Formation
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چکیده
منابع مشابه
Green fluorescent protein is a suitable reporter of tumor hypoxia despite an oxygen requirement for chromophore formation.
The oxygen requirement for chromophore formation potentially limits the use of green fluorescent protein as a reporter under hypoxic conditions. In the light of this, the applicability of a hypoxia-responsive enhanced green fluorescent protein (EGFP)-based system to the measurement of tumor hypoxia was tested in human HT 1080 fibrosarcoma cells stably transfected with a destabilized EGFP vector...
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ژورنال
عنوان ژورنال: Neoplasia
سال: 2001
ISSN: 1476-5586
DOI: 10.1038/sj.neo.7900192